Depression can feel isolating, overwhelming, and exhausting. When the weight of sadness lingers, it’s easy to believe you are alone in your struggles. But the truth is, you are not alone—God is with you. The Bible is filled with powerful words of comfort, strength, and hope that can help you navigate the darkest seasons of your life.

Affirmations rooted in Scripture can serve as a daily reminder of God’s promises. They help reframe negative thoughts, uplift your spirit, and strengthen your faith. If you’re struggling with depression or seeking encouragement, these 60 Bible affirmations will remind you of your worth, strength, and the unshakable love of God.

Related post: 15 Books to Read During Depression.

Finding Strength in God’s Promises

1. God is my refuge and strength; I will not be shaken. (Psalm 46:1)
2. The Lord renews my strength; I will soar on wings like eagles. (Isaiah 40:31)
3. I am never alone; God is always with me. (Deuteronomy 31:6)
4. The Lord’s plans for me are good and full of hope. (Jeremiah 29:11)
5. I cast all my burdens on God, and He sustains me. (Psalm 55:22)
6. I am strong in the Lord and in His mighty power. (Ephesians 6:10)
7. God is my help; I will not be afraid. (Isaiah 41:10)
8. I walk by faith, not by sight. (2 Corinthians 5:7)
9. The Lord restores my soul and leads me to peace. (Psalm 23:3)
10. I trust in God, and He directs my steps. (Proverbs 3:5-6)

God’s Love and Compassion for Me

11. I am deeply loved by God. (Romans 8:38-39)
12. Nothing can separate me from God’s love. (Romans 8:35)
13. I am fearfully and wonderfully made. (Psalm 139:14)
14. God rejoices over me with singing. (Zephaniah 3:17)
15. His love for me is everlasting. (Jeremiah 31:3)
16. I am a child of God, chosen and cherished. (1 John 3:1)
17. The Lord delights in me and sees me as precious. (Isaiah 43:4)
18. I am never forgotten; God has me in His hands. (Isaiah 49:16)
19. God is close to the brokenhearted and saves me. (Psalm 34:18)
20. His mercies are new every morning; I will find hope. (Lamentations 3:22-23)

Overcoming Fear and Anxiety

21. I will not fear, for God is with me. (Isaiah 41:13)
22. God gives me peace beyond understanding. (Philippians 4:7)
23. I will not worry about tomorrow; God holds my future. (Matthew 6:34)
24. The Lord fights for me, and I can rest in Him. (Exodus 14:14)
25. I am clothed with strength and dignity. (Proverbs 31:25)
26. I will not be anxious; I will pray and trust God. (Philippians 4:6)
27. Perfect love casts out all fear. (1 John 4:18)
28. God is my helper; I will not be afraid. (Hebrews 13:6)
29. My heart is steadfast, trusting in the Lord. (Psalm 112:7)
30. The Lord holds me with His righteous hand. (Isaiah 41:10)

Renewing My Mind and Spirit

31. I am transformed by the renewing of my mind. (Romans 12:2)
32. God’s Word is a light to my path. (Psalm 119:105)
33. I have the mind of Christ, filled with peace. (1 Corinthians 2:16)
34. My thoughts are fixed on what is true and noble. (Philippians 4:8)
35. The Lord gives me wisdom and understanding. (James 1:5)
36. I am no longer a slave to fear; I am free in Christ. (Romans 8:15)
37. God strengthens me when I feel weak. (2 Corinthians 12:9)
38. I take every thought captive to obey Christ. (2 Corinthians 10:5)
39. I will not let my heart be troubled; I trust in God. (John 14:27)
40. God’s Spirit renews my strength and fills me with hope. (Romans 15:13)

Healing and Restoration

41. The Lord heals my broken heart and binds my wounds. (Psalm 147:3)
42. By His stripes, I am healed. (Isaiah 53:5)
43. The joy of the Lord is my strength. (Nehemiah 8:10)
44. God gives me beauty for ashes. (Isaiah 61:3)
45. He restores my soul and makes me whole. (Psalm 23:3)
46. I am redeemed and set free by God’s grace. (Ephesians 1:7)
47. I will arise, for the Lord lifts me up. (Micah 7:8)
48. God is making all things new in my life. (Revelation 21:5)
49. The Lord is my portion, and I will hope in Him. (Lamentations 3:24)
50. He turns my mourning into joy. (Jeremiah 31:13)

Hope and Encouragement

51. My hope is in the Lord, and I will not be shaken. (Psalm 62:5)
52. I trust that God is working all things for my good. (Romans 8:28)
53. The Lord is my strength and my song. (Exodus 15:2)
54. I will not grow weary in doing good. (Galatians 6:9)
55. God’s grace is sufficient for me. (2 Corinthians 12:9)
56. The Lord is my light and salvation. (Psalm 27:1)
57. I will trust in the Lord with all my heart. (Proverbs 3:5)
58. I walk by faith, knowing God is in control. (Hebrews 11:1)
59. The Lord’s peace guards my heart and mind. (Philippians 4:7)
60. I am victorious in Christ. (1 Corinthians 15:57)

Using Biblical Affirmations in Daily Life

Speaking God’s Word over your life daily can shift your perspective and fill you with peace. Whether you write these affirmations in a journal, repeat them in prayer, or place them around your home, they will remind you of God’s unwavering love and faithfulness.

For extra encouragement, here are some recommendations:

• Bible Promise Book for Depression and Anxiety – A collection of comforting Scriptures and reflections
• 365 Devotions for Depression and Anxiety – Daily inspiration to uplift your spirit
• Scripture Cards for Daily Encouragement – A deck of beautifully designed Bible affirmations

Depression does not define you, and it does not have the final say. God’s truth is greater than any struggle, and He will carry you through every dark season. Let His words be a source of hope, strength, and renewal as you walk toward healing.